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The purpose of the therapy is to cause the development of the secondary sex characteristics of the desired sexsuch as breasts and a feminine pattern of hairfatand muscle distribution. This prolonged suppression is thought to result from a direct effect of estrogens on the Leydig cells. The American Journal of Surgical Pathology. This section needs additional citations for verification. However, in some people there may not be any growth at all. Post-adolescent growth is considerably slower and minimal by comparison.

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You might also need a mental health evaluation by a provider with expertise in transgender health.

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Hormone treatment for transgender women

Wagner 27 November Lower leg hair becomes less dense. GnRH modulators are highly effective for testosterone suppression in transgender women and have few or no side effects when sex hormone deficiency is avoided with concomitant estrogen therapy. Expert Opin Investig Drugs. The Molecular Biology of Cancer: Expert Opin Drug Saf.

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Current Sexual Health Reports. Spironolactone is an aldosterone antagonist and a relatively weak antiandrogen that blocks the AR and inhibits androgen biosynthesis. In patients in their teens or early twenties, antiandrogens prevent new facial hair from developing if testosterone levels are within the normal female range. Lesbian, Gay, Bisexual, and Transgender Healthcare: Retrieved 31 July

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